Comparison of molecular subtype distribution in triple-negative inflammatory and non-inflammatory breast cancers
Masuda, Hiroko × Baggerly, Keith A Wang, Ying Iwamoto, Takayuki Brewer, Takae Pusztai, Lajos Kai, Kazuharu Kogawa, Takahiro Finetti, Pascal Birnbaum, Daniel Dirix, Luc Woodward, Wendy A Reuben, James M Krishnamurthy, Savitri Symmans, W Fraser Van Laere, Steven Bertucci, François Hortobagyi, Gabriel N Ueno, Naoto T #
Biomed Central Ltd
Breast Cancer Research vol:15 issue:6
Because of its high rate of metastasis, inflammatory breast cancer (IBC) has a poor prognosis compared with non-inflammatory types of breast cancer (non-IBC). In a recent study, Lehmann and colleagues identified seven subtypes of triple-negative breast cancer (TNBC). We hypothesized that the distribution of TNBC subtypes differs between TN-IBC and TN-non-IBC. We determined the subtypes and compared clinical outcomes by subtype in TN-IBC and TN-non-IBC patients.