Personalised external aortic root support (PEARS) in Marfan syndrome: analysis of 1-9 year outcomes by intention-to-treat in a cohort of the first 30 consecutive patients to receive a novel tissue and valve-conserving procedure, compared with the published results of aortic root replacement
Treasure, Tom × Takkenberg, Johanna J M Golesworthy, Tal Rega, Filip Petrou, Mario Rosendahl, Ulrich Mohiaddin, Raad Rubens, Michael Thornton, Warren Lees, Belinda Pepper, John #
BMJ Pub. Group
Heart vol:100 issue:12 pages:969-75
Among people with Marfan syndrome who have a typical aortic root aneurysm, dissection is a characteristic cause of premature death. To pre-empt Type A dissection, composite root replacement with a mechanical valve became the standard of care in the 1980s and 1990s. This is being superseded by valve-sparing aortic root replacement to avoid lifelong anticoagulation. In 2004, a total root and valve-sparing procedure, personalised external aortic support, was introduced. We report here results among the first 30 recipients.