Title: Monoclonal antibodies targeting the antifibrinolytic activity of activated TAFI but not the anti-inflammatory activity on osteopontin and C5a
Authors: Semeraro, Fabrizio
Ammollo, Concetta T
Gils, Ann
Declerck, Paul
Colucci, Mario # ×
Issue Date: Oct-2013
Publisher: Blackwell Pub.
Series Title: Journal of Thrombosis and Haemostasis vol:11 issue:12 pages:2137-2147
Abstract: Recently, anti-TAFI monoclonal antibodies suggested to specifically inhibit plasmin-mediated TAFI activation were shown to stimulate fibrinolysis in vitro and in vivo, suggesting, in contrast to other findings, that plasmin-mediated TAFI activation plays an important role in fibrinolysis regulation.
ISSN: 1538-7933
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Therapeutic and Diagnostic Antibodies (+)
× corresponding author
# (joint) last author

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