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Title: Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: Performance evaluation of the new REGA version 3 and seven other tools
Authors: Pineda Pena, Andrea ×
Faria, Nuno Rodrigues
Imbrechts, Stijn
Libin, Pieter
Abecasis, Ana Barroso
Deforche, Koen
Gómez-López, Arley
Camacho, Ricardo Jorge
de Oliveira, Tulio
Vandamme, Anne-Mieke #
Issue Date: Oct-2013
Publisher: Elsevier Science
Series Title: Infection, Genetics and Evolution vol:19 pages:337-348
Article number: 10.1016/j.meegid.2013.04.032
Abstract: To investigate differences in pathogenesis, diagnosis and resistance pathways between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed to evaluate the performance of automated subtyping tools to classify the different subtypes and circulating recombinant forms using pol, the most sequenced region in clinical practice. We also present the upgraded version 3 of the Rega HIV subtyping tool (REGAv3).
URI: 
ISSN: 1567-1348
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
× corresponding author
# (joint) last author

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