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Title: Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort
Authors: Bartha, István ×
Assel, Matthias
Sloot, Peter Ma
Zazzi, Maurizio
Torti, Carlo
Schülter, Eugen
De Luca, Andrea
Sönnerborg, Anders
Abecasis, Ana B
Van Laethem, Kristel
Rosi, Andrea
Svärd, Jenny
Paredes, Roger
van de Vijver, David Amc
Vandamme, Anne-Mieke
Müller, Viktor #
Issue Date: Dec-2013
Publisher: BioMed Central
Series Title: BMC Infectious Diseases vol:13 pages:537
Article number: http://www.biomedcentral.com/1471-2334/13/537
Abstract: Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential route to drug resistance, we developed a bioinformatics pipeline to detect superinfection from routinely collected genotyping data, and assessed whether superinfection contributed to increased drug resistance in a large European cohort of viremic, drug treated patients.
URI: 
ISSN: 1471-2334
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
× corresponding author
# (joint) last author

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