IEEE MEMS, Date: 2014/01/26 - 2014/01/30, Location: San Francisco, CA, USA
Publication date:
2014-01-26
Pages:
272 -
275
ISSN:
9781479935086
Publisher:
IEEE
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Author:
Pérez Ruiz, Elena
Vandenryt, Thijs ; Witters, Daan ; Decrop, Deborah ; van Grinsven, Bart ; Spasic, Dragana ; Wagner, Patrick ; Lammertyn, Jeroen
Keywords:
Science & Technology, Technology, Engineering, Electrical & Electronic, Engineering, DROPLETS
Abstract:
In this paper the successful integration of heat-transfer resistance measurements with a digital microfluidic chip is shown. The integrated miniaturized platform allows the automated label-free detection of biomolecular interactions. To immobilize biomolecules on the hydrophobic chip surface, hydrophilic gold sensing patches are created by means of a recently described dry lift-off technique that leaves the chip surface unaffected. DNA melting analysis was performed for validating the integrated device. © 2014 IEEE.