Title: The esophageal mucosa and submucosa: immunohistology in GERD and Barrett's esophagus
Authors: Appelman, Henry D ×
Streutker, Catherine
Vieth, Michael
Neumann, Helmut
Neurath, Markus F
Upton, Melissa P
Sagaert, Xavier
Wang, Helen H
El-Zimaity, Hala
Abraham, Susan C
Bellizzi, Andrew M #
Issue Date: Oct-2013
Publisher: New York Academy of Sciences
Series Title: Annals of the New York Academy of Sciences vol:1300 issue:1 pages:144-165
Article number: 10.1111/nyas.12241
Abstract: This paper presents commentaries on the microscopic morphology of esophageal squamous epithelium; the frequency of duplication of the muscularis mucosae (MM) in Barrett's esophagus (BE); the significance of multilayered epithelium; whether cells in the lamina propria reflect those in the epithelium; how stem cells are identified in the squamous esophagus; dilated intercellular spaces; the metastasizing potential of early carcinoma-dependent, molecular or immunohistochemical tests that improve diagnosis; the role of immunohistochemistry IHC in grading of neoplasia in Barrett's esophagus and defining the risk of progression to adenocarcinoma; the roles of CDX1 and CDX2 in squamous and cardiac mucosa; and the role of desmosomal cadherins and lectins in squamous and cardiac mucosa.
ISSN: 0077-8923
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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