HIV-1 evolution in patients undergoing immunotherapy with Tat, Rev, and Nef expressing dendritic cells followed by treatment interruption
de Goede, Anna L × van Deutekom, Hanneke W M Vrancken, Bram Schutten, Martin Allard, Sabine D van Baalen, Carel A Osterhaus, Albert D M E Thielemans, Kris Aerts, Joeri L Keşmir, Can Lemey, Philippe Gruters, Rob A #
Gower Academic Journals
AIDS vol:27 issue:17 pages:2679-2689
This study aimed to evaluate HIV sequence evolution in whole genes and in CD8 T-cell epitope regions following immunotherapy and subsequent analytical treatment interruption (ATI). A second objective of this study was to analyze associations between vaccine-specific immune responses and epitope mutation rates.