Title: The use of transdermal buprenorphine to relieve radiotherapy-related pain in head and neck cancer patients
Authors: Menten, Joannes ×
Carpentier, Isabelle
Deschutter, Harlinde
Nuyts, Sandra
Van Beek, Karen #
Issue Date: Jul-2013
Publisher: Marcel Dekker
Series Title: Cancer Investigation vol:31 issue:6 pages:412-420
Article number: 10.3109/07357907.2013.800094
Abstract: Many head and neck cancer (HNC) patients experience painful therapy-related mucositis and dermatitis. This prospective observational study evaluated transdermal buprenorphine use in HNC patients to relieve treatment-related pain. During treatment with paracetamol or tramadol, visual analogue scale (VAS)-pain scores >30/100 occurred in 26/45 patients 4 weeks after starting cancer therapy, persisting for ≥2 weeks after treatment. These patients subsequently received transdermal buprenorphine. Pain therapy should be more accurately up-titrated to the maximum recommended dose (140 μg/hr) where necessary to maintain pain scores ≤30/100 and, for some patients, should be continued for 6 weeks after the last cancer treatment day.
ISSN: 0735-7907
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Experimental Radiotherapy
× corresponding author
# (joint) last author

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