Title: Exposure of HIV-1 to a combination of two carbohydrate-binding agents markedly delays drug resistance development and selects for virus strains with compromised fitness
Authors: Mathys, Leen ×
Balzarini, Jan #
Issue Date: Mar-2014
Publisher: Oxford University Press
Series Title: The Journal of Antimicrobial Chemotherapy vol:69 pages:582-593
Abstract: We investigated the effect of combining two potent carbohydrate-binding agents (CBAs) with a complementary resistance profile (based on different N-glycan deletion selections in the HIV envelope glycoprotein gp120) on drug resistance development and viral fitness.
ISSN: 0305-7453
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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