Novel intergenotype human norovirus recombinant GII.16/GII.3 in Bangladesh
Nahar, Shamsun × Afrad, Mokibul Hassan Matthijnssens, Jelle Rahman, Mohammed Ziaur Momtaz, Zehadee Yasmin, Rahena Jubair, Mohammad Faruque, Abu Syed Golam Choudhuri, Mohammad Sahabuddin Kabir Azim, Tasnim Rahman, Mustafizur #
Infection, Genetics and Evolution vol:20 issue:4 pages:325-329
Noroviruses (NoVs) are one of the major etiological agents of acute gastroenteritis in all age groups. In this study, we identified an intergenotype NoV recombinant strain in the fecal specimens of two male infants with acute diarrhea in Bangladesh. Phylogenetic analysis showed that the identified strains were recombinant NoV strains with a GII.3 capsid and a GII.16 polymerase gene. The recombination breakpoint was located in the ORF1/ORF2 overlap region. To the best of our knowledge this is the first report of a NoV recombinant GII.16/GII.3 strain worldwide.