Title: Pyridazine derivatives. Part 40: Reactivity of 5-alkynylpyridazin-3(2H)-ones toward hydrochloric acid
Authors: Coelho, A ×
Novoa de Armas, Hector
Peeters, OM
Blaton, Norbert
Alvarado, M
Sotelo, E #
Issue Date: May-2005
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:61 issue:20 pages:4785-4791
Abstract: 5-Alkynylpyridazin-3(2H)-ones or 5-(2-chloroalkenyl)pyridazin-3(2H)-ones were isolated during the cleavage of the methoxymethyl group in a series of 5 -alkynyl -2- methoxymethylpyridazin-3(2H) -ones by treatment with hydrochloric acid. The efficient and selective cleavage of the methoxymethyl group in these compounds can be performed under mild conditions by employing aluminium chloride. © 2005 Elsevier Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biocrystallography
× corresponding author
# (joint) last author

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