Effectiveness and tolerability of second-line therapy with vildagliptin vs. other oral agents in type 2 diabetes: A real-life worldwide observational study (EDGE)
Mathieu, Chantal × Barnett, A H Brath, H Conget, I de Castro, J J Göke, R Márquez Rodriguez, E Nilsson, P M Pagkalos, E Penfornis, A Schaper, N C Wangnoo, S K Kothny, W Bader, G #
International Journal of Clinical Practice vol:67 issue:10 pages:947-56
Real-life studies are needed to confirm the clinical relevance of findings from randomised controlled trials (RCTs). This study aimed to assess the effectiveness and tolerability of vildagliptin add-on vs. other oral antihyperglycaemic drugs (OADs) added to OAD monotherapy in a real-life setting, and to explore the advantages and limitations of large-scale 'pragmatic' trials.