Title: Solid-phase synthesis of 2',5'-oligoadenylates containing 3'-fluorinated ribose
Authors: Kovacs, T ×
Van Aerschot, Arthur
Herdewijn, Piet
Torrence, PF #
Issue Date: 1995
Publisher: Marcel dekker inc
Series Title: Nucleosides & nucleotides vol:14 issue:6 pages:1259-1267
Abstract: 2',5'-phosphodiester bond-linked oligoadenylate trimers with 3'-fluoro-3'-deoxyadenosine residues incorporated at specific positions of the nucleotide sequence were synthesized by the solid phase phosphite triester (phosphoramidite) method. The syntheses were in the 2' to 5' direction and were performed manually using commercially available microcolumns. The oligonucleotides were 5'-end phosphorylated on the support before deprotection.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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