Title: Practical method for the parallel synthesis of 2 '-amido-2 '-deoxyadenosines
Authors: Link, A ×
van Calenbergh, S
Herdewijn, Piet #
Issue Date: Jul-1998
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron letters vol:39 issue:29 pages:5175-5176
Abstract: A new synthetic strategy for the simple and high yielding preparation of arrays of 2'-amido-2'-deoxyadenosine derivatives ready for biological testing without the need for chromatographic purification is described. Acids are coupled to the Kenner or Ellman safety catch linker, respectively, activated by cyanomethylation and subsequently transferred to the 2'-amino group of 2'-amino-2'-deoxyadenosine. (C) 1998 Elsevier Science Ltd. All rights reserved.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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