Mesothelin levels in urine are affected by glomerular leakage and tubular reabsorption
Hollevoet, Kevin Speeckaert, Marijn M Decavele, An-Sofie Vanholder, Raymond van Meerbeeck, Jan P Delanghe, Joris R # ×
CIG Media Group
Clinical Lung Cancer vol:13 issue:6 pages:470-4
Mesothelin is a soluble biomarker of malignant mesothelioma. Levels in serum, however, are also influenced by other factors, including age and glomerular filtration rate (GFR). The measurement of mesothelin in urine has recently gained interest, but the renal handling of this protein has not been sufficiently examined.