Title: A new program for analyzing RNA interference
Authors: Vareková, Radka Svobodová ×
Bradác, Ivan
Plchút, Martin
Skrdla, Michal
Wacenovsky, Michael
Mahr, Helmuth
Mayer, Georg
Tanner, Herbert
Brugger, Hermann
Withalm, Josef
Lederer, Peter
Huber, Heinrich
Gierlinger, Gerhard
Graf, Ronald
Tafer, Hakim
Hofacker, Ivo
Schuster, Peter
Polcík, Martin #
Issue Date: Apr-2008
Publisher: Elsevier Science Publishers
Series Title: Computer Methods and Programs in Biomedicine vol:90 issue:1 pages:89-94
Article number: 10.1016/j.cmpb.2007.12.001
Abstract: RNA interference (RNAi) has become an important tool to study and utilize gene silencing by introducing short interfering RNA (siRNA). In order to predict the most efficient siRNAs, a new software tool, RNA Workbench (RNAWB), has been designed and is freely available (after registration) on In addition to the standard selection rules, RNAWB includes the possibility of statistical analyses of the applied selection rules (criteria). The role of RNA secondary structures in the RNA interference process as well as the application of sequence rules are discussed to show the applicability of the software.
ISSN: 0169-2607
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Cardiovascular Sciences - miscellaneous
× corresponding author
# (joint) last author

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