Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer
Kerns, Sarah L × Stock, Richard G Stone, Nelson N Blacksburg, Seth R Rath, Lynda Vega, Ana Fachal, Laura Gómez-Caamaño, Antonio De Ruysscher, Dirk Lammering, Guido Parliament, Matthew Blackshaw, Michael Sia, Michael Cesaretti, Jamie Terk, Mitchell Hixson, Rosetta Rosenstein, Barry S Ostrer, Harry #
Elsevier Science Publishers
Radiotherapy and Oncology vol:107 issue:3 pages:372-6
Rectal bleeding can occur following radiotherapy for prostate cancer and negatively impacts quality of life for cancer survivors. Treatment and clinical factors do not fully predict rectal bleeding, and genetic factors may be important.