Characterization of tumor heterogeneity using dynamic contrast enhanced CT and FDG-PET in non-small cell lung cancer
van Elmpt, Wouter × Das, Marco Hüllner, Martin Sharifi, Hoda Zegers, Catharina M L Reymen, Bart Lambin, Philippe Wildberger, Joachim E Troost, Esther G C Veit-Haibach, Patrick De Ruysscher, Dirk #
Elsevier Science Publishers
Radiotherapy and Oncology vol:109 issue:1 pages:65-70
Dynamic contrast-enhanced CT (DCE-CT) quantifies vasculature properties of tumors, whereas static FDG-PET/CT defines metabolic activity. Both imaging modalities are capable of showing intra-tumor heterogeneity. We investigated differences in vasculature properties within primary non-small cell lung cancer (NSCLC) tumors measured by DCE-CT and metabolic activity from FDG-PET/CT.