Title: Fast-atom bombardment mass spectrometric study of SATE Foscarnet prodrugs and of a series of Foscarnet-AZT conjugates
Authors: Rozenski, Jef ×
Meier, Chris
Aubagnac, Jean-Louis
Astier, René
Herdewijn, Piet
Imbach, Jean-Louis
Gosselin, Gilles #
Issue Date: 1997
Publisher: John wiley & sons ltd
Series Title: Rapid communications in mass spectrometry vol:11 issue:11 pages:1212-1218
Abstract: The mass spectrometric behaviour of a series of new derivatives of Foscarnet was studied with fast-atom bombardment and collision-induced dissociation experiments in positive- and negative-ion modes. For the compounds esterified with a 2-(S-pivaloyl)thioethyl [tert-butyl)SATE] group a rearrangement of the thioester linkage with expulsion of 60 u dominates the fragmentation pattern. (C) 1997 by John Wiley & Sons, Ltd.
ISSN: 0951-4198
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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