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Nucleosides, Nucleotides & Nucleic Acids

Publication date: 1998-01-01
Volume: 17 Pages: 1681 - 1684
Publisher: Marcel Dekker

Author:

Efimtseva, EV
Victorova, LS ; Rodionov, AA ; Ermolinsky, BS ; Fomitcheva, MV ; Tunitskaya, VL ; Mikhailov, SN ; Oivanen, M ; Van Aerschot, Arthur ; Herdewijn, Piet

Keywords:

transfer-rna, 0601 Biochemistry and Cell Biology, Organic Chemistry, 3101 Biochemistry and cell biology, 3404 Medicinal and biomolecular chemistry

Abstract:

A high yield synthesis of different O-ribofuranosylnucleosides has been achieved. Kinetics of the acid-catalysed hydrolysis of disaccharide nucleosides has been studied. Chemical and enzymatic incorporation of 2'-O-ribofuranosylnucleoside residue into oligonucleotides was investigated.