Title: Enantioselective approach to the synthesis of cyclohexane carbocyclic nucleosides
Authors: Wang, Jing
Busson, Roger
Blaton, Norbert
Rozenski, Jef
Herdewijn, Piet # ×
Issue Date: May-1998
Publisher: Amer chemical soc
Series Title: Journal of Organic Chemistry vol:63 issue:9 pages:3051-3058
Abstract: (R)-(-)-Carvone was used as starting material for the synthesis of a new series of 2-(hydroxymethyl)cyclohexane-1,3-diol nucleosides. The enantioselective precursors of the nucleoside analogues were obtained via a stereo-and regioselective hydroboration reaction. The compounds have equatorial oriented base moieties despite the presence of three other axial substituents.
ISSN: 0022-3263
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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