Title: Synthesis of thymidine from 5-iodo-2'-deoxyuridine
Authors: Herdewijn, Piet ×
Kerremans, L
Wigerinck, P
Vandendriessche, F
Van Aerschot, Arthur #
Issue Date: Aug-1991
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron letters vol:32 issue:34 pages:4397-4400
Abstract: A simple, high yield synthesis of thymidine from 5-iodo-2'-deoxyuridine is described, using tetramethyltin and tetrakis(triphenylphosphine)palladium(0) in hexamethylphoshoric triamide. Likewise, 5-phenyl- and 5-vinyl-2'-deoxyuridine can be obtained, and through reduction of the latter the 5-ethyl analogue is also at hand.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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