Title: Synthesis, enzymatic stability and physicochemical properties of oligonucleotides containing a N-cyanoguanidine linkage
Authors: Pannecouque, Christophe ×
Vandendriessche, F
Rozenski, Jef
Janssen, Gerardus
Busson, Roger
Van Aerschot, Arthur
Claes, Paul
Herdewijn, Piet #
Issue Date: Jun-1994
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:50 issue:24 pages:7231-7246
Abstract: Nucleoside dimers with a N-cyanoguanidine linkage were synthesized and used as building blocks for oligonucleotide synthesis. Oligonucleotides composed of alternating phosphodiester and cyanoguanidine functions are still able to hybridize with a complementary natural oligodeoxynucleotide.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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