Title: Susceptibility to stress induced visceral hypersensitivity in maternally separated rats is transferred across generations
Authors: van den Wijngaard, R M ×
Stanisor, O I
van Diest, S A
Welting, O
Wouters, Mira
Cailotto, C
de Jonge, W J
Boeckxstaens, Guy #
Issue Date: Dec-2013
Publisher: Blackwell Science
Series Title: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society vol:25 issue:12 pages:e780-90
Article number: 10.1111/nmo.12202
Abstract: In irritable bowel syndrome (IBS), familial clustering and transfer across generations may largely depend on environmental factors but this is difficult to establish in the human setting. Therefore, we aimed to set up a relevant animal model. We investigated whether susceptibility to stress induced visceral hypersensitivity in maternally separated (MS) Long Evans rats can be transferred across generations without further separation protocols and, if so, whether this depends on maternal care.
ISSN: 1350-1925
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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