Title: Synthesis and antiviral activity of acyclic analogues of 1,5-anhydrohexitol nucleosides using Mitsunobu reaction
Authors: Hossain, Nafizal
Rozenski, Jef
De Clercq, Erik
Herdewijn, Piet # ×
Issue Date: Oct-1996
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:52 issue:43 pages:13655-13670
Abstract: Starting from protected hexenetriol, acyclic analogues of the 1,5-anhydrohexitol nucleosides were synthesized. The reaction sequence involved a stereoselective Sharpless dihydroxylation and a Mitsunobu-type alkylation of the nucleoside bases. The compounds did not show antiviral activity. Copyright (C) 1996 Elsevier Science Ltd
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
Cell Metabolism
Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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