Title: Anaplastic large-cell lymphoma
Authors: Inghirami, Giorgio ×
Pileri, Stefano A
European T-Cell Lymphoma Study Group #
Contributors: Tousseyn, Thomas
Issue Date: Aug-2011
Publisher: Grune & Stratton
Series Title: Seminars in Diagnostic Pathology vol:28 issue:3 pages:190-201
Abstract: The concept of anaplastic large-cell lymphoma (ALCL) has changed over the years because of a stream of new information and novel understanding regarding the cell of origin, biology, genetics, and clinical features of these neoplasms. This new information has led to the current classification proposed by the expert reviewers of the World Health Organization. The objective of this review is to present the most updated information on the cytologic and histologic features of these entities, with a special reference to diagnostic algorithms. A detailed description of the genetic aberrations and the pathogenetic mechanisms leading to transformation is presented. The clinical features of ALCL and novel tailored strategies are briefly illustrated.
ISSN: 0740-2570
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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