Title: Structural requirements for stable binding of technetium-99m to derivatives of triglycine
Authors: Vanbilloen, HP ×
Busson, Roger
Verbruggen, AM #
Issue Date: Feb-2001
Publisher: John wiley & sons ltd
Series Title: Journal of labelled compounds & radiopharmaceuticals vol:44 issue:2 pages:99-111
Abstract: To study the importance of the thiol function of mercaptoacetyltriglycine (MAG3) for complexing technetium, we investigated a number of derivatives wherein the thiol function of MAG3, is replaced by other metal binding groups such as 3-nitropropionyl, thiophene-2-carbonyl, pyrrole-2-carbonyl, acetoacetyl, hydroxyacetyl, picolyl or aminoacetyl. These groups have the potential to form a bond with Tc via a free electron pair or the loss of a proton.
ISSN: 0362-4803
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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