Angewandte Chemie - International Edition
Author:
Keywords:
XNA - 320683;info:eu-repo/grantAgreement/EC/FP7/320683, Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, gene expression, hypoxanthine, nucleic acids, thymidylate synthetase, uracil, BUILDING-BLOCKS, NUCLEIC-ACIDS, OLIGONUCLEOTIDES, REPLICATION, RECOGNITION, NUCLEOSIDE, Arabinose, Base Sequence, Catalytic Domain, Cyclohexenes, DNA, Escherichia coli, Escherichia coli Proteins, Hypoxanthine, Nucleotides, Sugar Alcohols, Thymidylate Synthase, Xenobiotics, 03 Chemical Sciences, Organic Chemistry, 34 Chemical sciences
Abstract:
Hereditary information, coded in two bases, can be conveyed to DNA in vivo in the form of cyclohexenyl nucleic acid (CeNA), arabinofuranosyl nucleic acid (AraNA), and hexitol nucleic acid (HNA) messages. It was thus demonstrated that a binary genetic cassette can be used for the title process.