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Title: Relationship between social behavior, cognition and communication in children with 22q11.2 deletion syndrome
Authors: Van Den Heuvel, Ellen
Swillen, Ann
Manders, Eric
Zink, Inge
Issue Date: 2013
Conference: VCFS EF edition:20 location:Dublin date:19-21 July 2013
Abstract: Deficits in social behavior are increasingly being investigated in children with 22q11.2 deletion syndrome. These studies allow us to clarify the overlap and differences with autistic like behavior. Furthermore social failure is mentioned as a risk factor for the development of idiopathic schizophrenia. Research showed that individuals with 22q11.2 DS are very susceptible to the development of this psychiatric disorder. This study describes the social difficulties mentioned by parents. The relationship with cognitive and communicative development is being explored.
We assessed social responsiveness in children with 22q11.2 DS (chronological age 6 to 12 years old) by means of a parental questionnaire the Social Responsiveness Scale (SRS, Roeyers et al., 2011, Constantio & Gruber, 2005). In the presentation, we will give an overview of the social deficits found in a group of children with 22q11.2 DS compared to mental age matched controls. The relationship with various aspects of cognition and linguistic parameters will be discussed. Social problems are common in children with 22q11.2 DS and might be related to other developmental domains such as communication and cognition. More in depth research on language use in social context may provide a pathway for improving social skills in these children.
Publication status: published
KU Leuven publication type: IMa
Appears in Collections:Research Group Experimental Oto-rhino-laryngology
Department of Human Genetics - miscellaneous
Life Sciences TMMA

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