Title: Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis
Authors: Gold, Ralf ×
Kappos, Ludwig
Arnold, Douglas L
Bar-Or, Amit
Giovannoni, Gavin
Selmaj, Krzysztof
Tornatore, Carlo
Sweetser, Marianne T
Yang, Minhua
Sheikh, Sarah I
Dawson, Katherine T
DEFINE Study Investigators #
Contributors: Dubois, Bénédicte
Issue Date: Sep-2012
Series Title: New England Journal of Medicine vol:367 issue:12 pages:1098-107
Abstract: BG-12 (dimethyl fumarate) was shown to have antiinflammatory and cytoprotective properties in preclinical experiments and to result in significant reductions in disease activity on magnetic resonance imaging (MRI) in a phase 2, placebo-controlled study involving patients with relapsing-remitting multiple sclerosis.
ISSN: 0028-4793
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Neuroimmunology
× corresponding author
# (joint) last author

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