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Title: 5-(thien-2-yl)-2'-deoxyuridine - a new and potent inhibitor of herpes-simplex virus type-1 replication
Authors: Wigerinck, P
Van Aerschot, Arthur
De Clercq, Erik
Herdewijn, Piet #
Issue Date: 1991
Publisher: Marcel dekker inc
Host Document: Nucleosides & nucleotides pages:585-586
Conference: International Round Table on Nucleoside, Nucleotides and their Biological Applications edition:9 location:Uppsala, Sweden date:29 July-3 August 1990
Abstract: 5-(Thien-2-yl)-2'-deoxyuridine, synthesized by coupling of 5-iodo-2'-deoxyuridine with 2-trimethylstannylthiophene in the presence of a Pd catalyst, shows potent anti-HSV-1 activity in vitro.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Medicinal Chemistry (Rega Institute)
Cell Metabolism
Laboratory of Virology and Chemotherapy (Rega Institute)
# (joint) last author

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