Title: Synthesis of enantiomeric-pure cyclohexenyl nucleoside building blocks for oligonucleotide synthesis
Authors: Gu, P
Griebel, C
Van Aerschot, Arthur
Rozenski, Jef
Busson, Roger
Gais, HJ
Herdewijn, Piet # ×
Issue Date: 2004
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:60 issue:9 pages:2111-2123
Abstract: Lipases were used for the resolution of (+/-) (4aR, 7R, 8aS)-2-phenyl-4a,7,8,8a-tetrahydro-4H-1,3-benzodioxine. This separation was carried out on preparative scale and used for the synthesis of eight phosphoramidites of cyclohexenyl nucleosides (D- and L-series). (C) 2004 Elsevier Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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