Title: Antidiarrheic activity of sclerocarya-birrea bark extract and its active tannin constituent in rats
Authors: Galvez, J ×
Zarzuelo, A
Crespo, Me
Utrilla, Mp
Jimenez, J
Spiessens, Carl
de Witte, Peter #
Issue Date: Dec-1991
Publisher: John wiley & sons ltd
Series Title: Phytotherapy research vol:5 issue:6 pages:276-278
Abstract: The antidiarrhoeic activity of the bark of Sclerocarya birrea was investigated. The lyophilized decoction demonstrated antidiarrhoeic activity in experimental models of diarrhoea induced by magnesium sulphate and sodium picosulphate. This antidiarrhoeic activity was related to an inhibition of intestinal transit rather than to inhibition of net secretion of fluid and electrolytes provoked by the laxative agents. A condensed tannin was isolated from the crude drug which produced inhibition in intestinal motility, and the monomer of which was identified as procyanidin.
ISSN: 0951-418X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Pharmaceutical Biology (-)
Assisted Reproductive Technology Laboratory (-)
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science