Title: Synthesis and antiviral activities of some new 5-heteroaromatic substituted derivatives of 2'-deoxyuridine
Authors: Liu, J ×
Van Aerschot, Arthur
Luyten, Ingrid
Wigerinck, Piet
Pannecouque, Christophe
Balzarini, Jan
De Clercq, Erik
Herdewijn, Piet #
Issue Date: 1995
Publisher: Marcel dekker inc
Host Document: Nucleosides & nucleotides vol:14 issue:3-5 pages:525-528
Conference: 11th International Round Table; Nucleosides, nucleotides and their biological applications location:Leuven, Belgium date:7-11 September 1994
Abstract: Eight new 5-heteroaromatic substituted analogues of 2'-deoxyuridine have been synthesized and evaluated for their inhibitory properties against a panel of different viruses. Several analogues containing a substituted thiophene moiety proved to be highly selective against herpes simplex virus type 1 (HSV-1).
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Medicinal Chemistry (Rega Institute)
Laboratory of Virology and Chemotherapy (Rega Institute)
Cell Metabolism
× corresponding author
# (joint) last author

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