Title: Synthesis and antiviral evaluation of 3'-substituted thymidine analogues derived from 3'-amino-3'-deoxythymidine
Authors: Pannecouque, Christophe
Van Poppel, K
Balzarini, Jan
Claes, Paul
De Clercq, Erik
Herdewijn, Piet
Issue Date: 1995
Publisher: Marcel dekker inc
Host Document: Nucleosides & nucleotides vol:14 issue:3-5 pages:541-544
Conference: 11th International Round Table on Nucleosides, Nucleotides and their Biological Applications location:Leuven, Belgium date:11-17 September 1994
Abstract: To assess the structure-activity relationship for antiviral activity, a series of 3'-deoxy-3'-N-functionalized thymidine analogues were synthesized. Several of these thymidine analogues show moderate in vitro activity against HIV-1 and HIV-2.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
Medicinal Chemistry (Rega Institute)
Formal and Computational Linguistics (ComForT), Leuven
Centre for Industrial Management / Traffic & Infrastructure
Cell Metabolism

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