Title: 3'-deoxy-2',3'-difluorothymidine, a nucleoside analogue
Authors: Das, AK ×
Mukhopadhyay, A
Das, N
Mazumdar, SK
Bertolasi, V
Van Aerschot, Arthur #
Issue Date: Oct-1996
Publisher: Munksgaard int publ ltd
Series Title: Acta crystallographica section c-crystal structure communications vol:52 pages:2615-2616
Abstract: The title compound, 1-(2,3-dideoxy-2, 3-difluoro-beta-D-ribopentofuranosyl)thymine, C10H12F2N2O4, consists of an almost planar heterocyclic base moiety oriented anti with respect to a puckered sugar moiety. The sugar pucker is T-2(3) and the N-glycosidic torsion angle is -119.6(2)degrees. The conformation of the O5' atom is +sc and the molecules are held together by a network of N-H ... O and O-H ... O hydrogen bonds.
ISSN: 2053-2296
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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