Title: DEM in Biological Physics: Simulating Yeast Colony Growth
Authors: Odenthal, Tim
Smeets, Bart
Sliogeryte, Kristina
Van Liedekerke, Paul
Tijskens, Engelbert
Issue Date: 30-Jun-2010
Conference: International PhD & Research Day of the International Fine Particles Reasearch Institute (IFPRI) location:Universite de Liege date:30th June 2010
Abstract: DEM in Biological Physics: Simulating Yeast Colony Growth

To gain deeper understanding of the properties of biological systems such as cell colonies and tissues, modeling techniques are of utmost importance. Especially interest in the mechanical aspects of tissue/cultures is increasing because of the various important influences they have on life and death of the cells and the organism.
To simulate these structures, we choose an individual cell based, mesh-free modeling technique to ensure physically meaningful, directly measurable model parameters. In addition, we can use basic DEMeter++ code, a discrete elements methods software developed at MeBioS, KU Leuven.
The poster outlines the basic software design goals, main modeling ideas and the early stages of the validation of the model. We find the model suitable to describe the early growth of yeast micro-colonies.
Publication status: published
KU Leuven publication type: IMa
Appears in Collections:Division of Mechatronics, Biostatistics and Sensors (MeBioS)
Mechanical Engineering - miscellaneous

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