Title: d(GCGTAGC), an equilibrium between a hairpin structure and an unusual duplex
Authors: Lescrinier, Eveline ×
Sheng, SQ
Schraml, Jan
Busson, Roger
Herdewijn, Piet #
Issue Date: 1999
Publisher: Marcel dekker inc
Series Title: Nucleosides nucleotides & nucleic acids vol:18 issue:11-12 pages:2721-2744
Abstract: The DNA heptamer d(GCGTAGC), as determined by NMR spectroscopy, occurs in aqueous solution in a temperature- and salt-dependent equilibrium between a monoloop hairpin (where the unpaired thymidine, forming the loop, is stacked on top of the guanine (G3) base) and a duplex with the unpaired thymidine residues from opposite strands intercalating and costacking between shared G:A pairs.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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