Title: Reduced ventricular proarrhythmic potential of the novel combined ion-channel blocker AZD1305 versus dofetilide in dogs with remodeled hearts
Authors: Johnson, Daniel
de Jong, Monique M J
Crijns, Harry J G M
Carlsson, Leif G
Volders, Paul G A # ×
Issue Date: Feb-2012
Publisher: Lippincott Williams & Wilkins
Series Title: Circulation. Arrhythmia and Electrophysiology vol:5 issue:1 pages:201-9
Article number: 10.1161/CIRCEP.111.963025
Abstract: AZD1305 is an investigational antiarrhythmic agent for management of atrial fibrillation. It blocks various cardiac ion currents at different potencies and has atrial-predominant electrophysiological effects. We investigated the electrophysiological and proarrhythmic effects of AZD1305 versus dofetilide in dogs with chronic complete atrioventricular block and myocardial hypertrophic remodeling.
ISSN: 1941-3149
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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