Title: Evaluation of androgen-induced effects on the uptake of [18F]FDG, [11C]choline and [11C]acetate in an androgen-sensitive and androgen-independent prostate cancer xenograft model
Authors: Emonds, Kimy M ×
Swinnen, Johan
Lerut, Evelyne
Koole, Michel
Mortelmans, Luc
Mottaghy, Felix M #
Issue Date: 2013
Publisher: SpringerOpen
Series Title: EJNMMI Research vol:3 issue:1 pages:31
Article number: 10.1186/2191-219X-3-31
Abstract: Androgen deprivation (AD) is generally used as a first-line palliative treatment in prostate cancer (PCa) patients with rising prostate-specific antigen (PSA) after primary therapy. To acquire an accurate detection of tumour viability following AD with positron emission tomography (PET), an androgen-independent uptake of tracers would be advantageous. Several metabolic PET tracers are employed for detecting recurrent PCa. We evaluated the effect of AD on the uptake of 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG), [11C]choline and [11C]acetate in vivo.
ISSN: 2191-219X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Lipid Metabolism and Cancer (+)
× corresponding author
# (joint) last author

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