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Title: Synthesis and biological evaluation of a series of new cyclohexenyl nucleosides
Authors: Gu, Ping Morral, J Wang, J Rozenski, Jef Van Aerschot, Arthur De Clercq, Erik Herdewijn, Piet # ×
Issue Date: 2003
Publisher: Marcel Dekker
Series Title: Nucleosides, Nucleotides & Nucleic Acids vol:22 issue:5-8 pages:845-847
Abstract: A series of cyclohexenyl nucleosides (1-8) were successfully prepared with moderate yield and their cytotoxicity and antiviral activity were investigated. Among the eight new compounds, only the diaminopurine analogue 8 showed pronounced activity against HSV-1, HSV-2.
Publication status: published
KU Leuven publication type: IT
Appears in Collections: Medicinal Chemistry (Rega Institute) Hypertension and Cardiovascular Epidemiology Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author
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