Title: Intervention strategies for emerging viruses: use of antivirals
Authors: Debing, Yannick
Jochmans, Dirk
Neyts, Johan # ×
Issue Date: Apr-2013
Publisher: Elsevier Ltd. * Current Opinion Journals
Series Title: Current Opinion in Virology vol:3 issue:2 pages:217-24
Article number: 10.1016/j.coviro.2013.03.001
Abstract: Today, small molecule antiviral drugs are available for the treatment of infections with herpesviruses, HIV, HBV and HCV as well as with influenza viruses. Ribavirin, a broad-spectrum (but aspecific) antiviral, has been approved for the treatment of infections with respiratory syncytial virus, HCV and Lassa virus. Yet, for many other viruses that cause life-threatening infections [most of which are considered emerging and/or neglected] there are no drugs available. Ideally, potent and broad-spectrum (i.e., pan-genus or pan-family virus activity) antiviral drugs should be developed whereby one drug could be used for the treatment of a number of such viral infections. We here review recent evolutions in the search for inhibitors of emerging and neglected RNA viruses.
ISSN: 1879-6257
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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