Title: Synthesis and antiviral evaluation of N-β-D-ribosides of ergot alkaloids
Authors: Kren, V ×
Piskala, A
Sedmera, P
Havlicek, V
Prikrylova, V
Witvrouw, Myriam
De Clercq, Erik #
Issue Date: 1997
Series Title: Nucleos Nucleot vol:16 pages:97-106
Abstract: N-β-D-Ribosides of agroclavine (1), elymoclavine (2), lysergene (4), lysergol (3), and 9,10-dihydrolysergol (5) were prepared by SnCl2 catalyzed ribosylation of their TMS derivatives with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose. None of the new compounds exhibited activity against HIV or other viruses tested.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
Molecular Virology and Gene Therapy
× corresponding author
# (joint) last author

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