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Title: Reduced cortisol metabolism during critical illness
Authors: Boonen, Eva ×
Vervenne, Hilke
Meersseman, Philippe
Andrew, Ruth
Mortier, Leentje
Declercq, Peter
Vanwijngaerden, Yoo-Mee
Spriet, Isabel
Wouters, Pieter
Vander Perre, Sarah
Langouche, Lies
Vanhorebeek, Ilse
Walker, Brian R
Van den Berghe, Greet #
Issue Date: Apr-2013
Series Title: New England Journal of Medicine vol:368 issue:16 pages:1477-1488
Article number: 10.1056/NEJMoa1214969
Abstract: Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may be due to reduced cortisol metabolism.
ISSN: 0028-4793
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Pharmaceutical & Pharmacological Sciences - miscellaneous
Laboratory of Intensive Care Medicine
Department of Cellular and Molecular Medicine - miscellaneous
× corresponding author
# (joint) last author

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