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Title: FDG-PET scan in potentially operable non-small cell lung cancer: do anatometabolic PET-CT fusion images improve the localisation of regional lymph node metastases? The Leuven Lung Cancer Group
Authors: Vansteenkiste, Johan ×
Stroobants, Sigrid
Dupont, Patrick
De Leyn, Paul
De Wever, Walter
Verbeken, Eric
Nuyts, Johan
Maes, Frederik
Bogaert, Jan
The Leuven Lung Cancer Group #
Contributors: Deneffe, Georges
Verschakelen, Johny
Nackaerts, Kristiaan
Van Raemdonck, Dirk
Bormans, Guy
De Groot, T
Crombez, D
Vleugels, S
Costermans, W
Vandermeulen, Dirk
Issue Date: 1998
Publisher: Springer-Verlag
Series Title: European Journal of Nuclear Medicine vol:25 issue:11 pages:1495-501
Abstract: Exact localisation of thoracic lymph nodes (LNs) on fluorine-18 fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) can be hampered by the paucity of anatomical landmarks. In non-small cell lung cancer (NSCLC) patients referred for locoregional LN staging, we prospectively examined to what extent localisation of LNs at PET reading could be improved by visual correlation with computed tomography (CT), or by anatometabolic PET+CT fusion images. Fifty-six patients with potentially operable NSCLC underwent CT, PET and surgical staging. Prospective reading was performed for CT, PET without CT, PET+CT visual correlation and PET+CT fusion. Reading was blinded to surgical pathology data and noted on a standard LN map. Surgical staging was available for 493 LN stations. In the evaluation per individual LN station, CT was accurate in 87%, PET in 91% and visual correlation and fusion in 93%. In the identification of the nodal stage, CT was correct in 28/56 patients (50%), PET in 37/56 (66%), visual correlation in 40/56 (71%), and fusion in 41/56 (73%). It is concluded that in the exact localisation of metastatic thoracic LNs, the accuracy of reading of PET is increased if the PET images can be visually correlated with CT images. PET+CT anatometabolic fusion images add only a marginal benefit compared with visual correlation.
Description: European Journal of Nuclear Medicine, vol. 25, no. 11, pp. 1495-1501, November 1998, Springer-Verlag
ISSN: 0340-6997
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
ESAT - PSI, Processing Speech and Images
Surgical Oncology
Anatomy Section (-)
Translational MRI (+)
Research Group Neurophysiology
Research Group Experimental Neurology
Thoracic Surgery
Laboratory for Cognitive Neurology
Nuclear Medicine & Molecular Imaging
× corresponding author
# (joint) last author

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