Title: Recent trends in the management of minor salivary gland carcinoma
Authors: Vander Poorten, Vincent ×
Hunt, Jennifer
Bradley, Patrick J.
Haigentz, Missak
Rinaldo, Alessandra
Mendenhall, William M.
Suarez, Carlos
Silver, Carl
Takes, Robert P.
Ferlito, Alfio #
Issue Date: Mar-2014
Publisher: J. Wiley
Series Title: Head & Neck vol:36 issue:3 pages:444-55
Article number: DOI 10.1002/HED
Abstract: The current management of minor salivary gland cancer is reviewed. These malignancies often present as a submucosal swelling and have been reported at all anatomic subsites of the head and neck. Modern imaging is essential in evaluating the location and the anatomic extent of disease. An incisional or punch biopsy determines the hsitologic type and grade. Recent advances in molecular biology have yielded diagnostic and potential therapeutic targets that may change our treatment in the future. Complete resection is the treatment of choice. Unfortunately, given the proximity of essential structures, the need to balance funtional and cosmetic with oncologic consequences can interfere with an adequate "clear margin". The neck should be treated when there is evidence of regional metastasis or when subclinical metastatic risk exceeds 15%. Surgery alone cures most low-stage, low-grade tumors, all other stages and grades require postoperative radiotherapy. Systemic treatment for locoregional and distant failure remains disappointing.
ISSN: 1043-3074
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Head and Neck Oncology (+)
× corresponding author
# (joint) last author

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