ITEM METADATA RECORD
Title: The changing scene of amyotrophic lateral sclerosis
Authors: Robberecht, Wim ×
Philips, Thomas #
Issue Date: Apr-2013
Publisher: Nature Pub. Group
Series Title: Nature reviews. Neuroscience vol:14 issue:4 pages:248-64
Article number: 10.1038/nrn3430
Abstract: Several recent breakthroughs have provided notable insights into the pathogenesis of amyotrophic lateral sclerosis (ALS), with some even shifting our thinking about this neurodegenerative disease and raising the question as to whether this disorder is a proteinopathy, a ribonucleopathy or both. In addition, these breakthroughs have revealed mechanistic links between ALS and frontotemporal dementia, as well as between ALS and other neurodegenerative diseases, such as the cerebellar atrophies, myotonic dystrophy and inclusion body myositis. Here, we summarize the new findings in ALS research, discuss what they have taught us about this disease and examine issues that are still outstanding.
URI: 
ISSN: 1471-003X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Neurobiology (Vesalius Research Center)
× corresponding author
# (joint) last author

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