Idiopathic membranous nephropathy: clinical and histologic prognostic features and treatment patterns over time at a tertiary referral center

Sprangers, Ben; Bomback, Andrew S; Cohen, Scott D; Radhakrishnan, Jai; Valeri, Anthony; Markowitz, Glen S; D'Agati, Vivette; Appel, Gerald B

doi:10.1159/000339628

Idiopathic membranous nephropathy: clinical and histologic prognostic features and treatment patterns over time at a tertiary referral center

Author:

Sprangers, Ben

Bomback, Andrew S ; Cohen, Scott D ; Radhakrishnan, Jai ; Valeri, Anthony ; Markowitz, Glen S ; D'Agati, Vivette ; Appel, Gerald B

Keywords:

Adolescent, Adrenal Cortex Hormones, Adult, Aged, Aged, 80 and over, Biopsy, Cohort Studies, Female, Glomerular Filtration Rate, Glomerulonephritis, Membranous, Humans, Hypertension, Immunosuppressive Agents, Kidney Failure, Chronic, Male, Middle Aged, Prognosis, Referral and Consultation, Remission Induction, Retrospective Studies, Time Factors, United States, Science & Technology, Life Sciences & Biomedicine, Urology & Nephrology, Idiopathic membranous nephropathy, Impaired renal function, End-stage renal disease, Corticosteroids, FOCAL SEGMENTAL GLOMERULOSCLEROSIS, NEPHROTIC SYNDROME, LUPUS NEPHRITIS, CRESCENTIC GLOMERULONEPHRITIS, CONTROLLED-TRIAL, RENAL PATHOLOGY, GLOMERULOPATHY, METHYLPREDNISOLONE, RACE/ETHNICITY, TRANSFORMATION, 1103 Clinical Sciences, 3202 Clinical sciences

Abstract:

Idiopathic membranous nephropathy (i-MN) is a leading cause of nephrotic syndrome in adults and results in end-stage renal disease in approximately one third of patients. There are few large, long-term US studies evaluating clinical and histologic prognostic factors in i-MN.