Acknowledging patient heterogeneity in economic evaluation : a systematic literature review
Grutters, Janneke P C × Sculpher, Mark Briggs, Andrew H Severens, Johan L Candel, Math J Stahl, James E De Ruysscher, Dirk Boer, Albert Ramaekers, Bram L T Joore, Manuela A #
Pharmacoeconomics vol:31 issue:2 pages:111-23
Patient heterogeneity is the part of variability that can be explained by certain patient characteristics (e.g. age, disease stage). Population reimbursement decisions that acknowledge patient heterogeneity could potentially save money and increase population health. To date, however, economic evaluations pay only limited attention to patient heterogeneity. The objective of the present paper is to provide a comprehensive overview of the current knowledge regarding patient heterogeneity within economic evaluation of healthcare programmes.